Lifecycles of Individual Subretinal Drusenoid Deposits and Evolution of Outer Retinal Atrophy in Age-Related Macular Degeneration
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چکیده
منابع مشابه
Macular Atrophy Development and Subretinal Drusenoid Deposits in Anti-Vascular Endothelial Growth Factor Treated Age-Related Macular Degeneration
Purpose To explore the association between presence of subretinal drusenoid deposits (SDD) at baseline in eyes with neovascular age-related macular degeneration (nAMD) with the development of macular atrophy (MA) during anti-vascular endothelial growth factor (VEGF) therapy. Methods There were 74 eyes without pre-existing MA receiving anti-VEGF therapy for nAMD for 2 years or longer analyzed....
متن کاملSubretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model.
PURPOSE To characterize the morphology, prevalence, and topography of subretinal drusenoid deposits, a candidate histological correlate of reticular pseudodrusen, with reference to basal linear deposit (BlinD), a specific lesion of age-related macular degeneration, and to propose a biogenesis model for both lesion. METHODS Donor eyes with median death-to-preservation of 2:40 hours were postfi...
متن کاملDrusen and Sub Retinal Drusenoid Deposits ( SDD ) in Age Related Macular Degeneration
Purpose: To review drusen and sub retinal drusenoid deposits in age related macular degeneration as regards their pathogenesis, morphology, differentiation and their importance as regards the visual prognosis of age related macular degeneration (AMD). Results: Each type of drusen or drusenoid deposits has a different visual prognosis, and the differentiation of them using multimodal imaging tes...
متن کاملThe Association Between Subretinal Drusenoid Deposits in Older Adults in Normal Macular Health and Incident Age-Related Macular Degeneration
PURPOSE Subretinal drusenoid deposits (SDD) have been associated with the progression to late age-related macular degeneration (AMD). To determine whether SDD in eyes in normal macular health increases risk for early AMD, this study examined the association between presence of SDD at baseline in a cohort of older adults in normal macular health and incident AMD 3 years later. METHODS Subjects...
متن کاملOuter retinal corrugations in age-related macular degeneration.
IMPORTANCE Optical coherence tomography (OCT) abnormalities of age-related macular degeneration (AMD) have not been fully characterized because of the complex morphology and a lack of correlative histologic studies. Expansion of our ability to interpret increasing attributes brings us closer to the goal of in vivo histologic analysis of the eye by OCT. OBJECTIVE To describe a new outer retina...
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ژورنال
عنوان ژورنال: Ophthalmology Retina
سال: 2020
ISSN: 2468-6530
DOI: 10.1016/j.oret.2019.10.012